HUMAN CHROMOSOME MAP OF LYMPHEDEMA-LYMPHANGIOGENESIS GENES: TEMPLATE FOR CURRENT AND FUTURE DISCOVERY

Lymphedema and Therapeutic Lymphangiogenesis

Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities. Lymphedema is divided into primary and secondary forms based on the underlying etiology. Despite substantial advances in both surgical and conservative techniques, therapeutic options for the management of lymphedema are limited. Although rarely lethal, lymphedem...

Down syndrome and the genes of human chromosome 21: current knowledge and future potentials

brachycephaly associated with premature closure of the coronal suture of the skull), and still others occur in adulthood or in the elderly (premature aging, dementia). The mature brain in DS exhibits gross abnormalities in morphology, including proportionally greater reductions in size of both cerebellum and hippocampus. The frontal lobe is smaller and cytoarchitectonic abnormalities include re...

Lymphangiogenesis: a potential new therapy for lymphedema?

At the level of the capillaries, the systemic circulation loses 2 to 4 L fluid and 100 g protein into the interstitium daily. This ultrafiltrate of the systemic capillaries is returned to the circulatory system by the lymphatics. The lymphatic vasculature is highly specialized to perform this service, beginning with the blind-ended lymphatic capillaries. These vessels are highly permeable to pr...

1 Lymphangiogenesis : A Potential New Therapy for Lymphedema ?

Editorial Lymphangiogenesis A Potential New Therapy for Lymphedema ?

At the level of the capillaries, the systemic circulation loses 2 to 4 L fluid and 100 g protein into the interstitium daily. This ultrafiltrate of the systemic capillaries is returned to the circulatory system by the lymphatics. The lymphatic vasculature is highly specialized to perform this service, beginning with the blind-ended lymphatic capillaries. These vessels are highly permeable to pr...